# Atlanta Falcons (2-4) Week 7 Preview vs San Francisco 49ers (6-0): Prediction, Depth Chart, Injuries, Odds Source page: https://profootballnewshub.com/nfl/news/atlanta-falcons-2-4-week-7-preview-vs-san-francisco-49ers-6-0-prediction-depth-chart-injur > The Atlanta Falcons try to climb out of a two-game hole against a San Francisco 49ers team that hasn't lost yet. Game details When Sunday, October 25, 2026 a... By Rhett Zone · Published 2026-10-25 16:06 UTC · Updated 2026-10-25 16:11 UTC _Drafted with AI from our own data and checked by an editor._ The [Atlanta Falcons](https://profootballnewshub.com/nfl/teams/atlanta-falcons) try to climb out of a two-game hole against a [San Francisco 49ers](https://profootballnewshub.com/nfl/teams/san-francisco-49ers) team that hasn't lost yet. ## Game details - When | Sunday, October 25, 2026 at 1:00 PM ET - Where | Mercedes-Benz Stadium - TV | Fox - Line | San Francisco 49ers -2.5 | O/U 49.5 (market view) - San Francisco 49ers record | 6-0 - Atlanta Falcons record | 2-4 ## Overview The Atlanta Falcons (2-4) host the San Francisco 49ers (6-0) on Sunday, October 25, 2026 at Mercedes-Benz Stadium, kickoff at 1:00 PM ET on Fox. Atlanta comes in on a two-game skid, dropping a 23-31 decision to the Chicago Bears in Week 6 after a 23-30 loss to the Baltimore Ravens the week before. San Francisco has won every game it's played, most recently a 23-17 home win over the Washington Commanders in Week 6. Atlanta's season has had swings — a 45-24 win at the New Orleans Saints in Week 4 and a 35-14 win at the Green Bay Packers in Week 3 sit alongside a 3-34 blowout loss to the Carolina Panthers in Week 2. San Francisco's wins have been steadier: 32-29 over the Seattle Seahawks, 24-14 over the Denver Broncos, 36-30 over the Arizona Cardinals and 35-13 over the Miami Dolphins, all stacked in a row without a loss anywhere in the mix. The edge here belongs to San Francisco, and it's not close on paper. The 49ers have outscored opponents 177-110 this season, while the Falcons sit at 142-153. The market has San Francisco favored by 2.5 with a total of 49.5, which lines up with a team that hasn't lost and an Atlanta squad trying to find its footing again. ## Key players [Bijan Robinson](https://profootballnewshub.com/nfl/players/bijan-robinson) leads the league with 785 scrimmage yards this season and has topped 115 scrimmage yards in three of his past four games, carrying a 17.5 DraftKings projection into Sunday. [Michael Penix Jr.](https://profootballnewshub.com/nfl/players/michael-penix-jr) threw for 225 yards and 3 touchdowns with a 108.8 rating in Week 6 and is chasing a fifth straight game with 220-plus passing yards and a touchdown pass. [Drake London](https://profootballnewshub.com/nfl/players/drake-london) has gone for 95-plus receiving yards in three of his last four outings and projects for 14.0 DraftKings points. [Brock Purdy](https://profootballnewshub.com/nfl/players/brock-purdy) completed 21 of 29 passes for 264 yards and a touchdown with a 111.9 rating in Week 6 and is tied for first in the league with 14 touchdown passes this season. [Christian McCaffrey](https://profootballnewshub.com/nfl/players/christian-mccaffrey) piled up 117 scrimmage yards and 2 rushing touchdowns in Week 6 and ranks second in scrimmage yards since 2017 with 13,519. ## Keys to the game Atlanta has to find a way to bottle up McCaffrey near the goal line, since he's chasing a sixth straight game against Atlanta with 130-plus scrimmage yards. The Falcons defense needs to make Purdy work for it through the air, because he's posted 2-plus touchdown passes in five of his past six games. Atlanta's offense needs Bijan Robinson to set the tone early and often given he's the league's leading scrimmage-yardage back this season. ## Fantasy angles Start Bijan Robinson with confidence — a 17.5 DraftKings projection and the league's top scrimmage-yardage mark this season make him Atlanta's clear focal point. Start Michael Penix Jr. — he's projected for 16.0 points and is working on a streak of five straight games with 220-plus passing yards and a touchdown pass. Start Drake London — a 14.0 projection fits a receiver who's cleared 95 receiving yards in three of his last four games. [Kyle Pitts Sr.](https://profootballnewshub.com/nfl/players/kyle-pitts-sr) is a start in the red zone — he caught two touchdown passes in Week 6 and is chasing a third straight game with a touchdown catch, even with a modest 9.0 projection. [Nick Folk](https://profootballnewshub.com/nfl/players/nick-folk) is a streaming option at kicker with an 8.0 projection, nothing more. ## Prediction The market lands on San Francisco 26, Atlanta's offense enough to keep it within the margin, but the 49ers' perfect record and scoring edge carry them to a 26-24 finish. San Francisco's balance between Purdy's efficiency and McCaffrey's history against Atlanta is the difference, while the Falcons' two-game skid proves too much to overcome at home. ## Injury report - Player | Team | Pos | Status - Christian Kirk | San Francisco 49ers | WR | Questionable - Deebo Samuel Sr. | San Francisco 49ers | WR | Out - Garret Wallow | San Francisco 49ers | LB | Out - Luke Gifford | San Francisco 49ers | LB | Out - Marques Sigle | San Francisco 49ers | S | Out - Mike Evans | San Francisco 49ers | WR | Out - Nick Bosa | San Francisco 49ers | DE | Out - Siran Neal | San Francisco 49ers | S | Questionable - Upton Stout | San Francisco 49ers | CB | Questionable - A.J. Terrell Jr. | Atlanta Falcons | CB | Questionable - Avieon Terrell | Atlanta Falcons | CB | Questionable - Beaux Collins | Atlanta Falcons | WR | Questionable - Billy Bowman Jr. | Atlanta Falcons | CB | Out - Brian Robinson Jr. | Atlanta Falcons | RB | Out - C.J. Henderson | Atlanta Falcons | CB | Questionable - Divine Deablo | Atlanta Falcons | LB | Out - Kendal Daniels | Atlanta Falcons | LB | Questionable - Michael Jerrell | Atlanta Falcons | OT | Out - Olamide Zaccheaus | Atlanta Falcons | WR | Questionable ## Depth chart - Pos | Atlanta Falcons - QB | Michael Penix Jr. - RB | Bijan Robinson, Brian Robinson Jr. - WR | Drake London, Jahan Dotson , Olamide Zaccheaus - TE | Kyle Pitts Sr. ## Recent results - Team | Last games - Atlanta Falcons | Wk6 L 23-31 vs Chicago Bears, Wk5 L 23-30 vs Baltimore Ravens, Wk4 W 45-24 vs New Orleans Saints More league notes: [Week 7 NFL Preview & Capsules](https://profootballnewshub.com/nfl/news/nfl-press-week-7-nfl-preview-capsules), from the NFL. [**Game page**](https://profootballnewshub.com/nfl/game/96) *Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. 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