# Indianapolis Colts (2-2) Week 5 Preview vs Pittsburgh Steelers (2-2): Prediction, Depth Chart, Injuries, Odds

Source page: https://profootballnewshub.com/nfl/news/colts-look-to-extend-win-streak-against-steelers-in-pittsburgh

> Indianapolis brings a two-game win streak into a rainy Acrisure Stadium matchup against Pittsburgh in Week 5.

By Rhett Zone · Published 2026-10-11 16:18 UTC

_Drafted with AI from our own data and checked by an editor._

Jonathan Taylor and a two-game winning streak roll into Pittsburgh, and the [Indianapolis Colts](https://profootballnewshub.com/nfl/teams/indianapolis-colts) have a real shot to make it three straight against a Steelers team that just lost its last outing.

## Game details

- When | Sunday, October 11, 2026 at 1:00 PM ET
- Where | Acrisure Stadium
- TV | CBS
- Line | Pittsburgh Steelers -3 | O/U 42 (market view)
- Indianapolis Colts record | 2-2
- Pittsburgh Steelers record | 2-2

## Overview

The Indianapolis Colts sit at 2-2 and carry a two-game win streak into Sunday's trip to Acrisure Stadium, having knocked off the Washington Commanders 30-13 and survived the Houston Texans 19-17 in back-to-back weeks. Before that stretch, Indianapolis dropped games to the Kansas City Chiefs and the Baltimore Ravens, so this team has shown it can bounce back fast. Points for sit at 102 against 104 allowed, a tight margin that matches a team still finding its identity.

The [Pittsburgh Steelers](https://profootballnewshub.com/nfl/teams/pittsburgh-steelers) are also 2-2 but limping in on a one-game losing skid after falling 24-27 to the Cleveland Browns last time out. Pittsburgh beat the Cincinnati Bengals 30-27 the week before that, but sandwiched around those two results is a 3-20 blowout loss to the New England Patriots that still stands out. Pittsburgh's scoring numbers, 77 points for against 87 allowed, lag behind Indianapolis's output this year.

The betting market has Pittsburgh as three-point favorites at home with a total of 42, which tells you oddsmakers see this as a competitive, not blowout, football game. Given the Colts' momentum and the Steelers coming off a loss, Indianapolis has the form edge walking into this one, even on the road.

## Key players

Jonathan Taylor is projected for 19.0 DraftKings points and is the engine of this Colts offense, the back Indianapolis needs touching the ball inside the twenty.

Daniel Jones, projected at 11.0 points, has to manage the Pittsburgh pass rush and find completions in what's expected to be wet, windy conditions.

Tyler Warren brings a 9.5-point projection at tight end and gives Jones a reliable target when the field shrinks near the goal line.

Aaron Rodgers is projected for 14.5 points and remains the Steelers' top offensive weapon, the guy who has to answer Indianapolis's balanced attack.

Jaylen Warren, projected at 11.5 points, is Pittsburgh's lead back and the one player who can keep drives alive if the rain turns this into a ground-and-pound affair.

## Keys to the game

Feed [Jonathan Taylor](https://profootballnewshub.com/nfl/players/jonathan-taylor) early and often, especially with drizzle and twelve mile-per-hour wind in the forecast making the passing game tougher to rely on.

Get [Tyler Warren](https://profootballnewshub.com/nfl/players/tyler-warren) involved in the red zone, because a tight end who can win on short routes is exactly what you want when field position gets cramped near the goal line.

Take advantage of a Pittsburgh secondary that's down [Jamel Dean](https://profootballnewshub.com/nfl/players/jamel-dean) and [DeShon Elliott](https://profootballnewshub.com/nfl/players/deshon-elliott), with [Jalen Ramsey](https://profootballnewshub.com/nfl/players/jalen-ramsey) questionable, by attacking early and often before the Steelers can adjust.

## Fantasy angles

Start Jonathan Taylor without hesitation. A 19.0-point projection, the highest number on this slate for either team, and a wet-weather game script that should mean more carries, not fewer.

Start Tyler Warren in any format that rewards targets. A 9.5-point projection at tight end with [Keenan Allen](https://profootballnewshub.com/nfl/players/keenan-allen) banged up and [Ashton Dulin](https://profootballnewshub.com/nfl/players/ashton-dulin) and [Will Mallory](https://profootballnewshub.com/nfl/players/will-mallory) out, Warren becomes an even bigger piece of this passing game.

Josh Downs is a fine flex play at 8.5 projected points, but keep expectations measured given the rain and wind could cap big plays through the air.

Be cautious with [Daniel Jones](https://profootballnewshub.com/nfl/players/daniel-jones) in any format needing a ceiling game. His 11.0 projection already reflects a run-heavy approach, and the weather doesn't help a passer trying to push the ball downfield.

Spencer Shrader is a streamer-only option at kicker. His 8.8 projection looks fine on paper, but 80 percent precipitation and steady wind make field goal reliability a real question mark Sunday.

## Prediction

The market has this one going to Pittsburgh 23-20, and that lines up with a Steelers team at home getting the slight nod despite its one-game skid. Indianapolis's two-game win streak and Jonathan Taylor's workload give the Colts every reason to believe they can flip that script, but in a game this tight, with rain in the air and both run games expected to carry the load, a three-point final feels about right.

## Injury report

- Player | Team | Pos | Status
- Keenan Allen | Indianapolis Colts | WR | Questionable
- Ashton Dulin | Indianapolis Colts | WR | Out
- Will Mallory | Indianapolis Colts | TE | Out
- Jaylon Carlies | Indianapolis Colts | LB | Out
- Arden Key | Indianapolis Colts | DE | Out
- Charvarius Ward | Indianapolis Colts | CB | Questionable
- Darius Slayton | Indianapolis Colts | WR | Questionable
- Rico Dowdle | Pittsburgh Steelers | RB | Questionable
- Michael Pittman Jr. | Pittsburgh Steelers | WR | Out
- Jamel Dean | Pittsburgh Steelers | CB | Out
- DeShon Elliott | Pittsburgh Steelers | S | Out
- Jalen Ramsey | Pittsburgh Steelers | CB | Questionable

## Depth chart

- Pos | Indianapolis Colts
- QB | Daniel Jones
- RB | Jonathan Taylor, Seth McGowan
- WR | Josh Downs, Keenan Allen, Laquon Treadwell
- TE | Tyler Warren

## Recent results

- Team | Last games
- Indianapolis Colts | Wk4 W 30-13 vs Washington Commanders, Wk3 W 19-17 vs Houston Texans, Wk2 L 30-33 vs Kansas City Chiefs

[**Game page**](https://profootballnewshub.com/nfl/game/72)

## In this story

- [Indianapolis Colts at Pittsburgh Steelers](https://profootballnewshub.com/nfl/game/72)
- [Indianapolis Colts](https://profootballnewshub.com/nfl/teams/indianapolis-colts)
- [Pittsburgh Steelers](https://profootballnewshub.com/nfl/teams/pittsburgh-steelers)
- [Aaron Rodgers](https://profootballnewshub.com/nfl/players/aaron-rodgers)
- [Arden Key](https://profootballnewshub.com/nfl/players/arden-key)
- [Ashton Dulin](https://profootballnewshub.com/nfl/players/ashton-dulin)
- [Charvarius Ward](https://profootballnewshub.com/nfl/players/charvarius-ward)
- [Daniel Jones](https://profootballnewshub.com/nfl/players/daniel-jones)
- [Darius Slayton](https://profootballnewshub.com/nfl/players/darius-slayton)
- [DeShon Elliott](https://profootballnewshub.com/nfl/players/deshon-elliott)
- [Jalen Ramsey](https://profootballnewshub.com/nfl/players/jalen-ramsey)
- [Jamel Dean](https://profootballnewshub.com/nfl/players/jamel-dean)
- [Jaylen Warren](https://profootballnewshub.com/nfl/players/jaylen-warren)
- [Jaylon Carlies](https://profootballnewshub.com/nfl/players/jaylon-carlies)
- [Jonathan Taylor](https://profootballnewshub.com/nfl/players/jonathan-taylor)
- [Josh Downs](https://profootballnewshub.com/nfl/players/josh-downs)
- [Keenan Allen](https://profootballnewshub.com/nfl/players/keenan-allen)
- [Laquon Treadwell](https://profootballnewshub.com/nfl/players/laquon-treadwell)
- [Michael Pittman Jr.](https://profootballnewshub.com/nfl/players/michael-pittman-jr)
- [Rico Dowdle](https://profootballnewshub.com/nfl/players/rico-dowdle)
- [Seth McGowan](https://profootballnewshub.com/nfl/players/seth-mcgowan)
- [Spencer Shrader](https://profootballnewshub.com/nfl/players/spencer-shrader)
- [Tyler Warren](https://profootballnewshub.com/nfl/players/tyler-warren)
- [Will Mallory](https://profootballnewshub.com/nfl/players/will-mallory)

*Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts), and checked against that data before it published automatically. Read how we use AI in our [editorial standards](https://profootballnewshub.com/editorial-standards).*

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