# Dallas Cowboys (4-5) Week 10 Preview vs San Francisco 49ers (7-1): Prediction, Depth Chart, Injuries, Odds Source page: https://profootballnewshub.com/nfl/news/dallas-cowboys-4-5-week-10-preview-vs-san-francisco-49ers-7-1-prediction-depth-chart-injur > Dallas Cowboys ride a one-game winning streak into a home showdown with the red-hot San Francisco 49ers at AT&T Stadium. Game details When Sunday, Novemb... By Rhett Zone ยท Published 2026-11-15 03:02 UTC _Drafted with AI from our own data and checked by an editor._ [Dallas Cowboys](https://profootballnewshub.com/nfl/teams/dallas-cowboys) ride a one-game winning streak into a home showdown with the red-hot [San Francisco 49ers](https://profootballnewshub.com/nfl/teams/san-francisco-49ers) at AT&T Stadium. ## Game details - When | Sunday, November 15, 2026 at 4:25 PM ET - Where | AT&T Stadium - TV | Fox - Line | San Francisco 49ers -4 | O/U 56 (market view) - San Francisco 49ers record | 7-1 - Dallas Cowboys record | 4-5 ## Overview The Dallas Cowboys sit at 4-5 and carry a one-game winning streak into Sunday's matchup, having outlasted the Indianapolis Colts 27-23 on the road in Week 9. Before that, Dallas dropped a 30-33 decision at home to the Arizona Cardinals, beat the Philadelphia Eagles 38-21 on the road, lost 13-23 at the Green Bay Packers, and fell 16-24 at home to the Tampa Bay Buccaneers. The offense has produced 246 points this season against 236 allowed. San Francisco comes in at 7-1 and winners of its last game, a 38-17 rout of the Las Vegas Raiders at home in Week 9. The 49ers' only blemish in that stretch came in a 20-29 loss at the Atlanta Falcons in Week 7, sandwiched by wins over the Washington Commanders (23-17), Seattle Seahawks (32-29) and Denver Broncos (24-14). San Francisco has outscored opponents 235-156 on the season. Kickoff is set for Sunday, November 15, 2026 at 4:25 PM ET at AT&T Stadium, with cloudy skies, 49 degrees and 8 mph wind in the forecast on Fox. The market makes San Francisco a 4.0-point favorite with a 56.0 total, and with the 49ers' defense allowing just 156 points on the season, the edge leans to the road team. Dallas will need its offense, which has won two of its past five, to keep pace. ## Key players [Dak Prescott](https://profootballnewshub.com/nfl/players/dak-prescott) passed for 335 yards and 2 touchdowns with a 114.2 rating in Week 9 and is projected for 20.0 DraftKings points as he aims for a 10th straight game with a touchdown pass. [CeeDee Lamb](https://profootballnewshub.com/nfl/players/ceedee-lamb) led the team with 10 catches for a season-high 195 yards and a touchdown in Week 9, carries a 22.0-point projection, and already has 641 career receptions, the most by a player under age 28 in NFL history. [Javonte Williams](https://profootballnewshub.com/nfl/players/javonte-williams) racked up 124 scrimmage yards and a rushing touchdown in Week 9, has found the end zone on the ground in six of his past seven games, and projects for 15.5 points. [George Pickens](https://profootballnewshub.com/nfl/players/george-pickens) lines up as one of Dallas's starting outside receivers alongside Lamb and [Ryan Flournoy](https://profootballnewshub.com/nfl/players/ryan-flournoy) and is projected for 11.5 DraftKings points. [Brandon Aubrey](https://profootballnewshub.com/nfl/players/brandon-aubrey), the Cowboys' kicker, carries an 8.8-point projection for Sunday's game. ## Keys to the game Protect Dak Prescott up front against a 49ers pass rush that's been disruptive on the road, with [Nick Bosa](https://profootballnewshub.com/nfl/players/nick-bosa) chasing a fourth straight road game with a tackle for loss and [DeForest Buckner](https://profootballnewshub.com/nfl/players/deforest-buckner) logging one in six of his past seven away outings. Keep feeding Javonte Williams, who has a rushing touchdown in six of his last seven games, to control the clock against a 49ers defense that forced multiple takeaways last week. Avoid giveaways in the secondary matchup, with cornerback [Renardo Green](https://profootballnewshub.com/nfl/players/renardo-green) coming off an interception last week and ranking tied for third in the league with 4 interceptions this season, and safety Malik Mustapha grabbing his first interception of the season. Start Dak Prescott with confidence at a 20.0-point projection; he's thrown a touchdown pass in nine straight games. CeeDee Lamb is an easy start at 22.0 points off his season-high 195-yard, touchdown performance in Week 9. Javonte Williams is in play as a start at 15.5 points given his rushing score in six of his last seven games. George Pickens profiles as a flex start at 11.5 points as Dallas's second starting wideout. Brandon Aubrey is a steady streaming option at kicker, projected for 8.8 points. ## Prediction The market lists San Francisco as a 4.0-point favorite with a projected score of 49ers 30, Cowboys 26, matching the 56.0 total. That line tracks with a 49ers team that's outscored opponents 235-156 this season against a Dallas squad still finding consistency at 4-5. ## Injury report - Player | Pos | Status - Devin Moore | CB | Questionable - Donovan Ezeiruaku | LB | Out - Jake Ferguson | TE | Out - Joey Porter Jr. | CB | Questionable - Jonathan Bullard | DT | Questionable - Jonathan Mingo | WR | Out - P.J. Locke | S | Out - Tyler Goodson | RB | Out - Alijah Clark | S | Questionable - Juanyeh Thomas | S | Doubtful ## Depth chart ### Offense - Pos | Dallas Cowboys - QB | Dak Prescott - RB | Javonte Williams - FB | Hunter Luepke - WR | CeeDee Lamb, George Pickens, Ryan Flournoy - TE | Jake Ferguson - LT | Tyler Guyton - LG | Tyler Smith - C | Cooper Beebe - RG | Tyler Booker - RT | Terence Steele ### Defense - Pos | Dallas Cowboys - LDE | Quinnen Williams - NT | Otito Ogbonnia - RDE | Kenny Clark - WLB | Rashan Gary - LILB | DeMarvion Overshown - RILB | Dee Winters - SLB | Donovan Ezeiruaku - LCB | Joey Porter Jr. - RCB | DaRon Bland - NB | Caleb Downs - SS | P.J. Locke - FS | Malik Hooker ## Recent results - Team | Last games - Dallas Cowboys | Wk9 W 27-23 vs Indianapolis Colts, Wk8 L 30-33 vs Arizona Cardinals, Wk7 W 38-21 vs Philadelphia Eagles More league notes: [Week 10 NFL Preview & Capsules](https://profootballnewshub.com/nfl/news/nfl-press-week-10-nfl-preview-capsules), from the NFL. [**Game page**](https://profootballnewshub.com/nfl/game/148) *Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our [editorial standards](https://profootballnewshub.com/editorial-standards).* From Pro Football News Hub. More at https://profootballnewshub.com/llms.txt