# Los Angeles Rams (5-4) Week 10 Preview vs Arizona Cardinals (3-6): Prediction, Depth Chart, Injuries, Odds

Source page: https://profootballnewshub.com/nfl/news/los-angeles-rams-5-4-week-10-preview-vs-arizona-cardinals-3-6-prediction-depth-chart-injur

> The Los Angeles Rams ride a three-game win streak into Arizona looking to avenge an early-season home loss to the Arizona Cardinals . Game details When Sunda...

By Rhett Zone · Published 2026-11-15 01:11 UTC

_Drafted with AI from our own data and checked by an editor._

The [Los Angeles Rams](https://profootballnewshub.com/nfl/teams/los-angeles-rams) ride a three-game win streak into Arizona looking to avenge an early-season home loss to the [Arizona Cardinals](https://profootballnewshub.com/nfl/teams/arizona-cardinals).

## Game details

- When | Sunday, November 15, 2026 at 4:05 PM ET
- Where | State Farm Stadium
- TV | CBS
- Line | Los Angeles Rams -9.5 | O/U 39.5 (market view)
- Los Angeles Rams record | 5-4
- Arizona Cardinals record | 3-6

## Overview

The Los Angeles Rams sit at 5-4 and have won three straight, including a 20-13 win at the Washington Commanders, a 24-9 win over the Los Angeles Chargers and a 35-21 win at the Las Vegas Raiders. Before that stretch they dropped back-to-back games, a 16-18 loss to the Arizona Cardinals and a 34-37 loss to the Buffalo Bills. Los Angeles has outscored opponents 214-181 on the season.

The Arizona Cardinals are 3-6 and have lost one straight after falling 3-17 at the Seattle Seahawks in Week 9. Before that they beat the Dallas Cowboys 33-30, lost 16-30 to the Denver Broncos, beat the Rams 18-16, and lost 21-45 to the Detroit Lions. Arizona has been outscored 255-178 this season.

The market has Los Angeles favored by 9.5 points, and that lines up with the shape of these two seasons. The Rams are rolling on a three-game winning streak while the Cardinals are coming off a one-game skid and have been outscored by 77 points on the year. Edge Rams.

## Key players

Quarterback [Matthew Stafford](https://profootballnewshub.com/nfl/players/matthew-stafford) threw for 228 yards and a touchdown in Week 9 and is going for a sixth straight game with a touchdown pass, having thrown one in 13 of his last 14 road starts; he threw for 222 yards with two touchdowns and a 113.4 rating in the earlier meeting with Arizona and is looking to make it four straight meetings with the Cardinals with two or more touchdown passes and a rating of 110 or better.

Running back [Kyren Williams](https://profootballnewshub.com/nfl/players/kyren-williams) has a rushing touchdown in two of his last three games and has topped 80 scrimmage yards in two of his last three meetings with the Cardinals.

[Blake Corum](https://profootballnewshub.com/nfl/players/blake-corum) led the Rams with 58 rushing yards and a touchdown in Week 9 and is chasing a sixth straight game with a touchdown; he's topped 70 scrimmage yards in two of his last three outings and scored in two of his last three meetings with Arizona, including a touchdown catch in the earlier matchup this season.

[Puka Nacua](https://profootballnewshub.com/nfl/players/puka-nacua), the Rams' top target in the passing game, did not practice this week but still carries the highest fantasy projection on the roster at 23.5 DraftKings points.

[Myles Garrett](https://profootballnewshub.com/nfl/players/myles-garrett) (knee, questionable) leads all players with 128.5 sacks since entering the NFL in 2017, and with a sack Sunday he can pass Pro Football Hall of Famer Jared Allen's 128.5 for second-most sacks in a player's first 10 seasons since 1982, trailing only Reggie White's 145; he also had three sacks and a forced fumble in Week 9 and is going for a seventh straight road game with a sack.

## Keys to the game

Slow down [Trey McBride](https://profootballnewshub.com/nfl/players/trey-mcbride) over the middle; the Cardinals tight end has caught seven or more passes in eleven straight games and is a security blanket for whoever is under center.

Hold up up front without guard [Steve Avila](https://profootballnewshub.com/nfl/players/steve-avila), who is out with a hamstring injury, and keep Stafford clean against Arizona's pass rush.

Make rookie quarterback [Carson Beck](https://profootballnewshub.com/nfl/players/carson-beck), who could be making his first career start, uncomfortable early with pressure and takeaways before he settles in.

## Fantasy angles

Start Puka Nacua with confidence; his 23.5-point projection leads the entire Rams offense this week.

Matthew Stafford is a strong starting option at 15.5 projected points, with a shot at a sixth straight game with a touchdown pass.

Kyren Williams projects for 14.0 points and has a rushing touchdown in two of his last three games, making him a solid flex play.

[Davante Adams](https://profootballnewshub.com/nfl/players/davante-adams) checks in at 11.5 projected points and is a reasonable complementary option in the passing game.

Blake Corum's 11.0 projection, paired with his current touchdown streak, makes him worth a flex look in deeper formats.

## Prediction

The betting market has Los Angeles favored by 9.5 points with a total of 39.5, pointing to a 25-15 final. That projection fits a Rams team riding a three-game win streak against a Cardinals team that's been outscored 255-178 this season.

## Injury report

- Player | Pos | Status
- Davis Allen | TE | Questionable
- Joe Cardona | LS | Questionable
- Kam Curl | S | Questionable
- Myles Garrett | DE | Questionable
- Steve Avila | OG | Out
- Terrance Ferguson | TE | Out
- Trent McDuffie | CB | Questionable
- Puka Nacua | WR | Did not practice (no game status yet)
- Tyler Higbee | TE | Limited in practice (no game status yet)
- Aaron Donald | DT | Did not practice (no game status yet)

## Depth chart

### Offense

- Pos | Los Angeles Rams
- QB | Matthew Stafford
- RB | Kyren Williams
- WR | Konata Mumpfield, Tutu Atwell , CJ Daniels
- TE | Tyler Higbee
- LT | Alaric Jackson
- LG | Beaux Limmer
- C | Coleman Shelton
- RG | Kevin Dotson
- RT | Warren McClendon Jr.

### Defense

- Pos | Los Angeles Rams
- LDE | Braden Fiske
- NT | Ty Hamilton
- RDE | Aaron Donald
- WLB | Byron Young
- LILB | Nate Landman
- RILB | Omar Speights
- SLB | Myles Garrett
- LCB | Josh Wallace
- RCB | Trent McDuffie
- NB | Quentin Lake
- SS | Kam Curl
- FS | Kamren Kinchens

## Recent results

- Team | Last games
- Los Angeles Rams | Wk9 W 20-13 vs Washington Commanders, Wk8 W 24-9 vs Los Angeles Chargers, Wk7 W 35-21 vs Las Vegas Raiders

More league notes: [What To Look For – Week 10](https://profootballnewshub.com/nfl/news/nfl-press-what-to-look-for-week-10), from the NFL.

[**Game page**](https://profootballnewshub.com/nfl/game/147)

*Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our [editorial standards](https://profootballnewshub.com/editorial-standards).*

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