# NFL Week 7: Indianapolis Colts (2-4) vs. Minnesota Vikings (5-0) Game Preview, Injury Report and Predictions

Source page: https://profootballnewshub.com/nfl/news/nfl-week-7-indianapolis-colts-2-4-vs-minnesota-vikings-5-0-game-preview-injury-report-and

> Minnesota's unbeaten Vikings host a reeling Indianapolis Colts team in Week 7, with Justin Jefferson closing in on a receiving-yards milestone.

By Rhett Zone · Published 2026-10-24 17:16 UTC

_Drafted with AI from our own data and checked by an editor._

[Justin Jefferson](https://profootballnewshub.com/nfl/players/justin-jefferson-min) chases NFL history as the unbeaten Vikings host a reeling Colts team.

The [Minnesota Vikings](https://profootballnewshub.com/nfl/teams/minnesota-vikings) enter Week 7 at 5-0 on a five-game winning streak, while the [Indianapolis Colts](https://profootballnewshub.com/nfl/teams/indianapolis-colts) sit at 2-4 and have dropped two straight. Minnesota hosts Indianapolis on Sunday, October 25, 2026 at 1:00 PM ET at U.S. Bank Stadium, with the game airing on CBS.

## Game details

- When | Sunday, October 25, 2026 at 1:00 PM ET
- Where | U.S. Bank Stadium
- TV | CBS
- Line | Minnesota Vikings -6.5 | O/U 41.5 (market view)
- Indianapolis Colts record | 2-4
- Minnesota Vikings record | 5-0

## The matchup

According to the NFL, Minnesota is 5-0 for just the second time in the past three seasons, having also opened that fast in 2024. The Vikings have won five in a row, including a 23-13 road win over the New Orleans Saints in Week 5 and a 15-10 home win over the Miami Dolphins in Week 4.

Indianapolis has lost two straight, falling 20-26 to the Tennessee Titans in Week 6 and 22-34 to the Pittsburgh Steelers in Week 5. [Daniel Jones](https://profootballnewshub.com/nfl/players/daniel-jones) threw for a season-high 269 yards and a touchdown in that loss to Tennessee, and he's topped 210 passing yards in four of his past five starts.

## Key matchups

[Jonathan Taylor](https://profootballnewshub.com/nfl/players/jonathan-taylor) is the name to watch near the goal line for Indianapolis. He posted a season-high 151 scrimmage yards with a rushing touchdown last week and is one of two AFC running backs, along with Derrick Henry, with seven rushing touchdowns this season. He's chasing his fourth straight road game with 80-plus scrimmage yards and has scored two-plus rushing touchdowns in two of his last three on the road. He can also become just the fourth player ever under age 28 with 20 career games of two-plus rushing touchdowns, a strong sign Indianapolis will keep feeding him inside the 20.

Justin Jefferson needs three receiving yards to pass Calvin Johnson for third-most receiving yards by a player in his first 100 career games in NFL history, per the NFL. He caught six passes for 79 yards and a touchdown in Week 5 and had seven catches for 137 yards in the last meeting between these two teams. On the other side, [Keenan Allen](https://profootballnewshub.com/nfl/players/keenan-allen) led the Colts with eight catches for 82 yards last week and has six-plus receptions, 80-plus yards and a touchdown in two of his last three games against Minnesota.

[Aaron Jones Sr.](https://profootballnewshub.com/nfl/players/aaron-jones-sr) led Minnesota with 113 rush yards and a touchdown in Week 5 and is chasing his fifth straight game with 90-plus scrimmage yards; he's scored in two of his last three at home. Linebacker Blake Cashman has recorded seven-plus tackles in 16 consecutive games, the longest active streak in the NFL, and led the Vikings with nine tackles and a tackle for loss in Week 5.

## Injuries that matter

Indianapolis is without wide receiver [Anthony Gould](https://profootballnewshub.com/nfl/players/anthony-gould) (concussion) and tight end [Tyler Warren](https://profootballnewshub.com/nfl/players/tyler-warren) (groin), both ruled out, along with cornerback [Sauce Gardner](https://profootballnewshub.com/nfl/players/sauce-gardner) (calf). Linebacker [Bryce Boettcher](https://profootballnewshub.com/nfl/players/bryce-boettcher) (groin), cornerback [Justin Walley](https://profootballnewshub.com/nfl/players/justin-walley) (knee), punter [Rigoberto Sanchez](https://profootballnewshub.com/nfl/players/rigoberto-sanchez) (foot) and linebacker [CJ Allen](https://profootballnewshub.com/nfl/players/cj-allen) (ankle) are all questionable. Linebacker [Austin Ajiake](https://profootballnewshub.com/nfl/players/austin-ajiake) was limited in practice and defensive tackle [DeForest Buckner](https://profootballnewshub.com/nfl/players/deforest-buckner) did not practice, though neither has a game status yet.

Minnesota's injury report is lighter. Running back [Jordan Mason](https://profootballnewshub.com/nfl/players/jordan-mason) (thumb) is questionable. Offensive tackle [Christian Darrisaw](https://profootballnewshub.com/nfl/players/christian-darrisaw) did not practice and safety [Harrison Smith](https://profootballnewshub.com/nfl/players/harrison-smith) was limited, but neither carries a game status at this point.

## Fantasy angles

Start Jonathan Taylor with confidence. He's projected for 16.0 DraftKings points and is averaging goal-line work that's produced seven rushing touchdowns already this season.

Justin Jefferson is projected for 13.0 points and is chasing a receiving-yards milestone against a Colts defense that's allowed him big games before, including 137 yards in the last meeting.

Aaron Jones Sr. carries a 14.0-point projection and has found the end zone in two of his last three home games, making him a strong start out of the Vikings backfield.

Keenan Allen's 10.0-point projection undersells his recent production; he's got five-plus catches in four of his five games this season and has produced big lines against Minnesota before.

[Kyler Murray](https://profootballnewshub.com/nfl/players/kyler-murray), projected for 13.0 points, has thrown a touchdown pass in two of his last three outings and adds rushing upside to his floor.

## The pick

The market has Minnesota favored by 6.5 with a total of 41.5, and the market score sits at Vikings 24, Colts 18. Minnesota's perfect start, its home scoring edge and Jefferson's pursuit of history give the Vikings the clear edge here, while Indianapolis will need Jonathan Taylor to keep pounding the ball inside the 20 just to keep this one competitive.

## Injury report

- Player | Team | Pos | Status
- Anthony Gould | Indianapolis Colts | WR | Out
- Bryce Boettcher | Indianapolis Colts | LB | Questionable
- Justin Walley | Indianapolis Colts | CB | Questionable
- Rigoberto Sanchez | Indianapolis Colts | P | Questionable
- Sauce Gardner | Indianapolis Colts | CB | Out
- Tyler Warren | Indianapolis Colts | TE | Out
- CJ Allen | Indianapolis Colts | LB | Questionable
- Austin Ajiake | Indianapolis Colts | LB | Limited in practice (no game status yet)
- DeForest Buckner | Indianapolis Colts | DT | Did not practice (no game status yet)
- Jordan Mason | Minnesota Vikings | RB | Questionable
- Christian Darrisaw | Minnesota Vikings | OT | Did not practice (no game status yet)
- Harrison Smith | Minnesota Vikings | S | Limited in practice (no game status yet)

## Projected starters

- Pos | Indianapolis Colts | Minnesota Vikings
- QB | Daniel Jones | Kyler Murray
- RB | Jonathan Taylor, Seth McGowan | Aaron Jones Sr., Demond Claiborne
- WR | Josh Downs, Keenan Allen, Laquon Treadwell | Justin Jefferson, Jordan Addison , Jauan Jennings
- TE | Tyler Warren | T.J. Hockenson

## Recent results

- Team | Last games
- Indianapolis Colts | Wk6 L 20-26 vs Tennessee Titans, Wk5 L 22-34 vs Pittsburgh Steelers, Wk4 W 30-13 vs Washington Commanders
- Minnesota Vikings | Wk5 W 23-13 vs New Orleans Saints, Wk4 W 15-10 vs Miami Dolphins, Wk3 W 23-16 vs Tampa Bay Buccaneers

More league notes: [Week 7 NFL Preview & Capsules](https://profootballnewshub.com/nfl/news/nfl-press-week-7-nfl-preview-capsules) and [What To Look For – Week 7](https://profootballnewshub.com/nfl/news/nfl-press-what-to-look-for-week-7), from the NFL.

[**Game page**](https://profootballnewshub.com/nfl/game/98)

*Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our [editorial standards](https://profootballnewshub.com/editorial-standards).*

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