The unbeaten Minnesota Vikings try to make it six straight when the reeling Indianapolis Colts come to U.S. Bank Stadium.
Game details
| When | Sunday, October 25, 2026 at 1:00 PM ET |
| Where | U.S. Bank Stadium |
| TV | CBS |
| Line | Minnesota Vikings -6.5 | O/U 41.5 (market view) |
| Indianapolis Colts record | 2-4 |
| Minnesota Vikings record | 5-0 |
Overview
The Minnesota Vikings welcome the Indianapolis Colts to U.S. Bank Stadium on Sunday, October 25, 2026, with kickoff at 1:00 PM ET on CBS. Minnesota enters at 5-0, winners of five straight, while Indianapolis sits at 2-4 and has dropped its last two.
Indianapolis has lost two in a row, falling 20-26 at home to the Tennessee Titans in Week 6 after a 22-34 road loss to the Pittsburgh Steelers in Week 5. Before that stretch, the Colts beat the Washington Commanders 30-13 and edged the Houston Texans 19-17, though a Week 2 loss to the Kansas City Chiefs, 30-33, shows the inconsistency that has marked their season.
Minnesota has rattled off five consecutive wins, including a 23-13 win at the New Orleans Saints in Week 5 and a 15-10 home win over the Miami Dolphins the week before that. The Vikings have outscored opponents 109-64 on the season, and the market has them favored by 6.5 points with a total of 41.5, which lines up with a defense that keeps finding ways to protect a perfect record.
Key players
Justin Jefferson leads the NFL with 8,738 receiving yards since entering the league in 2020, and he's within reach of three receiving yards that would push him past Pro Football Hall of Famer Calvin Johnson for third-most receiving yards by a player in his first 100 career games in NFL history.
Aaron Jones Sr. led Minnesota with 113 rushing yards and a touchdown in Week 5 and is chasing a fifth straight game with 90-plus scrimmage yards.
Kyler Murray completed 24 of 30 passes for 229 yards and a touchdown with a 109.6 rating while adding 51 rushing yards in Week 5, and he's thrown a touchdown pass in two of his past three.
Jonathan Taylor paced Indianapolis with a season-high 151 scrimmage yards and a rushing touchdown in Week 6, and he's one of two AFC running backs, along with Derrick Henry, with seven rushing touchdowns this season.
Daniel Jones threw for a season-high 269 yards and a touchdown in Week 6 and has topped 210 passing yards in four of his last five starts.
Keys to the game
Minnesota has to slow down Jonathan Taylor early, since he's one of just two AFC backs with seven rushing touchdowns this season and can wear a defense down in a hurry.
The Vikings need to get home on Daniel Jones, who's thrown for 210-plus yards in four of his last five outings, with Dallas Turner looking to stretch his streak of 0.5-plus sacks to five straight games.
Minnesota should keep leaning on Aaron Jones Sr. on the ground, since he's chasing a fifth straight game of 90-plus scrimmage yards and controlling the clock fits right into the Vikings' current form.
Fantasy angles
Aaron Jones Sr. is an easy start at 14.0 projected DraftKings points off the back of a 113-yard, one-touchdown showing in Week 5.
Justin Jefferson belongs in every lineup regardless of matchup, projected for 13.0 points after a six-catch, 79-yard, one-touchdown game in Week 5.
Kyler Murray is a solid starting option at 13.0 points, coming off a 229-yard, one-touchdown game through the air plus 51 yards on the ground.
Will Reichard is worth a look at kicker with a 9.8 projection, playing behind an offense that keeps finding the end zone.
Jordan Mason is questionable with a thumb injury and projected for just 9.0 points behind Aaron Jones Sr. in this backfield, making him a bench stash rather than a lineup play.
Prediction
The market sets this one at Minnesota Vikings 24, Indianapolis Colts 18, with the Vikings favored by 6.5 and the total at 41.5. That price lines up with the season so far: Minnesota's defense has allowed just 64 points through five games, and Indianapolis has been inconsistent on the road. Jonathan Taylor and Daniel Jones give the Colts a puncher's chance, but the Vikings' unbeaten run makes them the side to beat at U.S. Bank Stadium.
Injury report
| Player | Team | Pos | Status |
|---|---|---|---|
| Anthony Gould | Indianapolis Colts | WR | Out |
| Bryce Boettcher | Indianapolis Colts | LB | Questionable |
| Justin Walley | Indianapolis Colts | CB | Questionable |
| Rigoberto Sanchez | Indianapolis Colts | P | Questionable |
| Sauce Gardner | Indianapolis Colts | CB | Out |
| Tyler Warren | Indianapolis Colts | TE | Out |
| CJ Allen | Indianapolis Colts | LB | Questionable |
| Austin Ajiake | Indianapolis Colts | LB | Limited in practice (no game status yet) |
| DeForest Buckner | Indianapolis Colts | DT | Did not practice (no game status yet) |
| Jordan Mason | Minnesota Vikings | RB | Questionable |
| Christian Darrisaw | Minnesota Vikings | OT | Did not practice (no game status yet) |
| Harrison Smith | Minnesota Vikings | S | Limited in practice (no game status yet) |
Depth chart
| Pos | Minnesota Vikings |
|---|---|
| QB | Kyler Murray |
| RB | Aaron Jones Sr., Demond Claiborne |
| WR | Justin Jefferson, Jordan Addison, Jauan Jennings |
| TE | T.J. Hockenson |
Recent results
| Team | Last games |
|---|---|
| Minnesota Vikings | Wk5 W 23-13 at New Orleans Saints, Wk4 W 15-10 vs Miami Dolphins, Wk3 W 23-16 at Tampa Bay Buccaneers |
More league notes: Week 7 NFL Preview & Capsules and What To Look For – Week 7, from the NFL.
Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our editorial standards.