The New York Giants arrive in Houston looking to stop the bleeding, running into a Texans team riding two straight wins.
Game details
| When | Sunday, October 25, 2026 at 1:00 PM ET |
| Where | Reliant Stadium |
| TV | Fox |
| Line | Houston Texans -10.5 | O/U 42.5 (market view) |
| New York Giants record | 3-2-1 |
| Houston Texans record | 2-4 |
Overview
The New York Giants (3-2-1, L1) head to Reliant Stadium to face the Houston Texans (2-4, W2) on Sunday, October 25, 2026, with kickoff at 1:00 PM ET on Fox under cloudy skies near 80 degrees. Houston is favored by 10.5 points with the total set at 42.5, and the market sees the Texans pulling away.
New York dropped a 27-34 decision at home to the New Orleans Saints in Week 6, following a 27-27 tie at the Washington Commanders, a 36-24 win over the Arizona Cardinals, a 12-7 win over the Tennessee Titans and a 6-28 loss at the Los Angeles Rams. Houston enters on a two-game roll, beating the Jacksonville Jaguars 34-31 and the Tennessee Titans 26-3, after dropping three in a row to the Dallas Cowboys, Indianapolis Colts and Cincinnati Bengals.
The Texans have the juice right now. Will Anderson Jr. leads the NFL with 7.5 sacks, and quarterback C.J. Stroud is coming off a 312-yard, three-touchdown outing against Jacksonville. The Giants counter with Malik Nabers, who's been the best player on the field most weeks, but a banged-up secondary and front seven make this a tough spot on the road.
Key players
Malik Nabers torched the New Orleans Saints for 12 catches and 165 yards in Week 6, and he's got a touchdown catch in two of his past three games.
Isaiah Likely caught six passes for 99 yards and a score last week and is chasing his third straight game with 90-plus receiving yards and a touchdown.
Jameis Winston threw for 152 yards and a touchdown in Week 6 and has hit 250-plus passing yards with three-plus touchdown passes in two of his past three games.
C.J. Stroud completed 24 of 34 passes for 312 yards and three touchdowns with a 116.3 rating in Week 6, and he's aiming for a fourth straight game with a 65-percent completion rate, 260-plus yards, a touchdown pass and a 105-plus rating.
Will Anderson Jr. leads the NFL with 7.5 sacks this season and has posted at least half a sack in five of his past six games.
Keys to the game
Keep Jameis Winston upright behind an offensive line already dealing with questionable tags on Jermaine Eluemunor and Marcus Mbow and a limited practice for Andrew Thomas.
Get Malik Nabers the ball early and keep feeding him, since he's been the one consistent weapon New York has had all season.
Find a way to slow down Nico Collins and Jaylin Noel, a tall order with Greg Newsome II out and both Paulson Adebo and Jevon Holland questionable in the secondary.
Fantasy angles
Malik Nabers is a clear start at an 18.0-point projection, the kind of target volume you want near the goal line no matter the matchup.
Isaiah Likely projects for 13.5 points and is red-zone trustworthy coming off a game with 90-plus yards and a touchdown.
Jameis Winston checks in at a 14.0-point projection and is worth rostering given his recent touchdown streak.
Cam Skattebo's 7.5-point projection makes him a touchdown-dependent flex rather than a must-start against this Houston defense.
Dominic Zvada is a fine streaming option at kicker with a 6.8-point projection if you need the position filled.
Prediction
The market has this one going to Houston, 27-16, and that lines up with where both teams are trending. The Texans have the firepower and the two-game streak, while New York's injury list on both lines makes it tough to see the Giants keeping pace on the road.
Injury report
| Player | Team | Pos | Status |
|---|---|---|---|
| Greg Newsome II | New York Giants | CB | Out |
| Jermaine Eluemunor | New York Giants | OT | Questionable |
| Jevon Holland | New York Giants | S | Questionable |
| Marcus Mbow | New York Giants | OT | Questionable |
| Paulson Adebo | New York Giants | CB | Questionable |
| Theo Johnson | New York Giants | TE | Doubtful |
| Tremaine Edmunds | New York Giants | LB | Out |
| Tyler Nubin | New York Giants | S | Questionable |
| Andrew Thomas | New York Giants | OT | Limited in practice (no game status yet) |
| Blake Fisher | Houston Texans | OT | Out |
| David Montgomery | Houston Texans | RB | Out |
| Jalen Pitre | Houston Texans | S | Out |
| Reed Blankenship | Houston Texans | S | Out |
| Tank Dell | Houston Texans | WR | Questionable |
| Jadeveon Clowney | Houston Texans | DE | Did not practice (no game status yet) |
| Nico Collins | Houston Texans | WR | Limited in practice (no game status yet) |
| Will Anderson Jr. | Houston Texans | DE | Limited in practice (no game status yet) |
Depth chart
| Pos | New York Giants |
|---|---|
| QB | J.J. McCarthy |
| RB | Cam Skattebo, Tyrone Tracy Jr. |
| WR | Malik Nabers, Malachi Fields, Darnell Mooney |
| TE | Isaiah Likely |
Recent results
| Team | Last games |
|---|---|
| New York Giants | Wk6 L 27-34 vs New Orleans Saints, Wk5 T 27-27 vs Washington Commanders, Wk4 W 36-24 vs Arizona Cardinals |
Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our editorial standards.