Sunday's Biggest Absences
Green Bay Packers running back Josh Jacobs, San Francisco 49ers wide receiver Mike Evans, Seattle Seahawks quarterback Sam Darnold and Minnesota Vikings quarterback Kyler Murray are all out for Week 10.
Tennessee Titans wide receiver Carnell Tate, Dallas Cowboys running back Tyler Goodson and Vikings tight end T.J. Hockenson are also sidelined, while Carolina Panthers running back Jonathon Brooks is doubtful.
In total, 64 players have been ruled out across Sunday's slate, with several more listed as questionable heading into kickoff.
Josh Jacobs (Out) vs Minnesota Vikings
Josh Jacobs did not practice this week with a finger injury and will not play against the Minnesota Vikings.
MarShawn Lloyd, Kaleb Johnson and Pierre Strong Jr. are all projected at 3.5 News Hub Fantasy points in his absence, which points to a split workload rather than one clear lead back.
With none of the three separated in projection, none of them belong in fantasy lineups this week, and this backfield should be avoided until a hierarchy emerges.
Mike Evans (Out) at Dallas Cowboys
Mike Evans is out with an Achilles injury after not practicing this week and will miss the trip to face the Dallas Cowboys.
Deebo Samuel Sr. is projected for 9.5 News Hub Fantasy points and becomes the top receiving option in Evans' place, making him a fine fantasy start.
Keenan Allen, projected at 7.0 points, is also worth a look as a flex play, while Demarcus Robinson's 5.5-point projection keeps him in deeper-league consideration only.
Sam Darnold (Out) at Las Vegas Raiders
Sam Darnold did not practice this week with a rib injury and is out against the Las Vegas Raiders.
Drew Lock steps in and is projected for 14.5 News Hub Fantasy points, making him a viable streaming option at quarterback this week.
Jalen Milroe is third on the depth chart with a 0.0 projection and has no fantasy value in this matchup.
Kyler Murray (Out) at Green Bay Packers
Kyler Murray is out with a hamstring injury after not practicing this week, and the Minnesota Vikings turn back to Kirk Cousins against the Green Bay Packers.
Cousins carries a strong 16.5-point News Hub Fantasy projection and is a clear streaming option at the position this week.
Carson Wentz (3.0 points) and Max Brosmer (0.5 points) are well behind him and hold no fantasy relevance.
Carnell Tate (Out) vs Jacksonville Jaguars
Carnell Tate did not practice this week because of a shoulder injury and is out for the Tennessee Titans against the Jacksonville Jaguars.
Wan'Dale Robinson is projected for 6.5 News Hub Fantasy points and becomes the top receiving option, making him a reasonable depth add.
Chimere Dike (3.0 points) and Elic Ayomanor (3.5 points) are both projected too low to trust in fantasy lineups this week.
Jonathon Brooks (Doubtful) at New Orleans Saints
Jonathon Brooks is doubtful with a groin injury after a limited practice week and is unlikely to play for the Carolina Panthers against the New Orleans Saints.
Chuba Hubbard is projected for 15.5 News Hub Fantasy points and is the clear lead back if Brooks sits, making him a strong fantasy start.
Trevor Etienne and AJ Dillon are both projected at just 1.0 point and carry no standalone fantasy value behind him.
Tyler Goodson (Out) vs San Francisco 49ers
Tyler Goodson did not practice this week with an ankle injury and is out for the Dallas Cowboys against the San Francisco 49ers.
Javonte Williams is projected for 15.5 News Hub Fantasy points and is the clear lead back in Goodson's absence, making him a confident start.
Malik Davis is projected at 0.0 points and Emari Demercado has no projection listed, leaving neither in play for fantasy purposes.
T.J. Hockenson (Out) at Green Bay Packers
T.J. Hockenson is out with a wrist injury after not practicing this week, leaving a thin tight end group for the Minnesota Vikings against the Green Bay Packers.
Ben Yurosek, Gavin Bartholomew and Josh Oliver are projected between 1.0 and 1.5 News Hub Fantasy points, none of which supports a fantasy start.
This group should be avoided in all fantasy formats until a clearer lead option emerges.
Questionable to watch
Kenneth Walker III (groin) did not practice at all this week.
Garrett Wilson (concussion) had a full practice week.
Travis Etienne Jr. (hamstring) had a full practice week.
Omar Cooper Jr. (ankle) had a full practice week.
David Montgomery (groin) had a full practice week.
Denzel Boston (toe) was a limited participant in practice this week.
Full injury report
New England Patriots at Detroit Lions
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Ben Brown | C | NE | Out | Knee |
| Cade Mays | C | DET | Out | Ankle |
| Carlton Davis III | CB | NE | Out | Knee |
| D.J. Reed | CB | DET | Out | Hip |
| Kerby Joseph | S | DET | Out | Knee |
| TreVeyon Henderson | RB | NE | Out | Illness |
| A.J. Brown | WR | NE | Questionable | Ankle |
| Amon-Ra St. Brown | WR | DET | Questionable | Rib |
| Brenden Schooler | S | NE | Questionable | Hamstring |
| Cameron Latu | TE | NE | Questionable | Back |
| Charles Woods | CB | NE | Questionable | Hamstring |
| Greg Van Roten | OG | NE | Questionable | Hamstring |
| Kevin Byard | S | NE | Questionable | Chest |
| Reggie Gilliam | FB | NE | Questionable | Knee |
| Rhamondre Stevenson | RB | NE | Questionable | Knee |
| Sione Vaki | RB | DET | Questionable | Ankle |
| Walter Rouse | OT | NE | Questionable | Concussion |
Kansas City Chiefs at Atlanta Falcons
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Zachariah Branch | WR | ATL | Out | Hamstring |
| Jaylon Moore | OT | KC | Out | Ankle |
| Omarr Norman-Lott | DT | KC | Out | Knee |
| Peter Woods | DT | KC | Out | Neck |
| Divine Deablo | LB | ATL | Doubtful | Forearm |
| Kenneth Walker III | RB | KC | Questionable | Groin |
| Jaydn Ott | RB | KC | Questionable | Hamstring |
| Gervon Dexter Sr. | DT | ATL | Questionable | Illness |
| James Pearce Jr. | LB | ATL | Questionable | Back |
| Josh Woods | LB | ATL | Questionable | Ankle |
| Mansoor Delane | CB | KC | Questionable | Shoulder |
Houston Texans at Cleveland Browns
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Marvin Harrison Jr. | WR | HOU | Out | Hamstring |
| Michael Burton | FB | CLE | Out | Calf |
| Brevin Jordan | TE | HOU | Out | Finger |
| Azeez Al-Shaair | LB | HOU | Out | Groin |
| Danielle Hunter | DE | HOU | Out | Hamstring |
| Keylan Rutledge | OG | HOU | Out | Neck |
| Ronnie Hickman | S | CLE | Out | Concussion |
| David Montgomery | RB | HOU | Questionable | Groin |
| Denzel Boston | WR | CLE | Questionable | Toe |
| Jake Hummel | LB | HOU | Questionable | Groin |
| Jaylin Smith | CB | HOU | Questionable | Hamstring |
| Trent Brown | OT | HOU | Questionable | Wrist |
| Will Anderson Jr. | DE | HOU | Questionable | Ankle |
| Wyatt Teller | OG | HOU | Questionable | Illness |
Minnesota Vikings at Green Bay Packers
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Josh Jacobs | RB | GB | Out | Finger |
| Kyler Murray | QB | MIN | Out | Hamstring |
| T.J. Hockenson | TE | MIN | Out | Wrist |
| Jauan Jennings | WR | MIN | Out | Calf |
| Josh Whyle | TE | GB | Out | Concussion |
| Blake Cashman | LB | MIN | Out | Concussion |
| Micah Parsons | DE | GB | Out | Knee |
| Sean Rhyan | OG | GB | Out | Ankle |
| Tyrion Ingram-Dawkins | DE | MIN | Out | Ankle |
| Zaire Franklin | LB | GB | Doubtful | Shin |
| Jordan Addison | WR | MIN | Questionable | Thumb |
| Chris Brooks | RB | GB | Questionable | Ankle |
| Skyy Moore | WR | GB | Questionable | Ankle |
| Javon Bullard | S | GB | Questionable | Ankle |
| Joshua Metellus | S | MIN | Questionable | Shoulder |
| Kevin Zeitler | OG | GB | Questionable | Ankle |
| Kyle Van Noy | LB | MIN | Questionable | Calf |
| Lukas Van Ness | DE | GB | Questionable | Back |
| Travis Glover | OT | GB | Questionable | Knee |
| Xavier McKinney | S | GB | Questionable | Foot |
Jacksonville Jaguars at Tennessee Titans
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Carnell Tate | WR | TEN | Out | Shoulder |
| Anthony Hill Jr. | LB | TEN | Out | Neck |
| B.J. Green II | DE | JAX | Out | Forearm |
| Cody Barton | LB | TEN | Out | Concussion |
| Jessie Bates III | S | JAX | Out | Not injury related - resting player |
| Jordan Davis | DT | JAX | Out | Not injury related - resting player |
| Peter Skoronski | OG | TEN | Out | Hamstring |
| Tommy Townsend | P | TEN | Out | Knee |
| Tyjae Spears | RB | TEN | Questionable | Knee |
| Robert Hainsey | C | JAX | Questionable | Concussion |
Miami Dolphins at Indianapolis Colts
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Jared Wayne | WR | MIA | Out | Quadricep |
| Mo Alie-Cox | TE | IND | Out | Groin |
| Aaron Brewer | C | MIA | Out | Concussion |
| Akeem Davis-Gaither | LB | IND | Out | Knee |
| Jalen Travis | OT | IND | Out | Knee |
| Jaylon Carlies | LB | IND | Out | Neck |
| Jerry Tillery | DT | IND | Out | Calf |
| Luke Rhodes | LS | IND | Out | Hamstring |
| Chris Bell | WR | MIA | Doubtful | Knee |
| Will Mallory | TE | IND | Questionable | Hamstring |
| Arden Key | DE | IND | Questionable | Hamstring |
| Darrell Baker Jr. | CB | MIA | Questionable | Knee |
Carolina Panthers at New Orleans Saints
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| CJ Donaldson | RB | NO | Out | Shoulder |
| Bobby Okereke | LB | CAR | Out | Foot |
| Christen Miller | DT | NO | Out | Knee |
| Erik McCoy | C | NO | Out | Biceps |
| Taliese Fuaga | OT | NO | Out | Knee |
| Jonathon Brooks | RB | CAR | Doubtful | Groin |
| Mike Jackson | CB | CAR | Doubtful | Groin |
| Travis Etienne Jr. | RB | NO | Questionable | Hamstring |
| Xavier Legette | WR | CAR | Questionable | Knee |
| Brady Christensen | OG | CAR | Questionable | Hamstring |
| Jaelan Phillips | LB | CAR | Questionable | Hamstring |
| Martin Emerson Jr. | CB | NO | Questionable | Shin |
| Will Lee III | CB | CAR | Questionable | Hamstring |
Buffalo Bills at New York Jets
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Trevin Wallace | LB | NYJ | Out | Groin |
| Spencer Brown | OT | BUF | Doubtful | Ankle |
| Garrett Wilson | WR | NYJ | Questionable | Concussion |
| Omar Cooper Jr. | WR | NYJ | Questionable | Ankle |
| Adonai Mitchell | WR | NYJ | Questionable | Knee |
| Tyrell Shavers | WR | BUF | Questionable | Knee |
| Christian Benford | CB | BUF | Questionable | Wrist |
| Harrison Phillips | DT | NYJ | Questionable | Ankle |
| Jarvis Brownlee Jr. | CB | NYJ | Questionable | Illness |
| Jordan Hancock | CB | BUF | Questionable | Hamstring |
| Joseph Ossai | DE | NYJ | Questionable | Ankle |
| Nahshon Wright | CB | NYJ | Questionable | Back |
| Sam Franklin Jr. | S | BUF | Questionable | Shoulder |
| VJ Payne | S | NYJ | Questionable | Knee |
Seattle Seahawks at Las Vegas Raiders
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Sam Darnold | QB | SEA | Out | Ribs |
| Charles Cross | OT | SEA | Out | Ankle |
| Leonard Williams | DT | SEA | Out | Stinger |
| Quenton Nelson | OG | SEA | Out | Knee |
| Dont'e Thornton Jr. | WR | LV | Questionable | Back |
| Thomas Booker IV | DT | LV | Questionable | Ankle |
Los Angeles Rams at Arizona Cardinals
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Terrance Ferguson | TE | LAR | Out | Ankle |
| Hjalte Froholdt | C | ARI | Out | Concussion |
| Jon Gaines II | OG | ARI | Out | Ankle |
| Steve Avila | OG | LAR | Out | Hamstring |
| Zachary Carter | DT | ARI | Out | Knee |
| Davis Allen | TE | LAR | Questionable | Oblique |
| Hunter Long | TE | ARI | Questionable | Knee |
| Andrew Wingard | S | ARI | Questionable | Groin |
| Darius Robinson | DE | ARI | Questionable | Wrist |
| Jayden Williams | OT | ARI | Questionable | Knee |
| Joe Cardona | LS | LAR | Questionable | Ankle |
| Kam Curl | S | LAR | Questionable | Toe |
| Max Melton | CB | ARI | Questionable | Knee |
| Myles Garrett | DE | LAR | Questionable | Knee |
| Roy Lopez | DT | ARI | Questionable | Toe |
| Trent McDuffie | CB | LAR | Questionable | Back |
San Francisco 49ers at Dallas Cowboys
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Mike Evans | WR | SF | Out | Achilles |
| Tyler Goodson | RB | DAL | Out | Ankle |
| Jake Ferguson | TE | DAL | Out | Knee |
| Jonathan Mingo | WR | DAL | Out | Ankle |
| Donovan Ezeiruaku | LB | DAL | Out | Ankle |
| P.J. Locke | S | DAL | Out | Concussion |
| Juanyeh Thomas | S | DAL | Doubtful | Hamstring |
| Alijah Clark | S | DAL | Questionable | Illness |
| C.J. West | DT | SF | Questionable | Knee |
| DaRon Bland | CB | DAL | Questionable | Ankle |
| Deommodore Lenoir | CB | SF | Questionable | Foot |
| Devin Moore | CB | DAL | Questionable | Hip |
| Dre Greenlaw | LB | SF | Questionable | Knee |
| Joey Porter Jr. | CB | DAL | Questionable | Ankle |
| Jonathan Bullard | DT | DAL | Questionable | Calf |
| Nate Hobbs | CB | SF | Questionable | Groin |
| Renardo Green | CB | SF | Questionable | Back |
| Trent Williams | OT | SF | Questionable | Shoulder |
| Upton Stout | CB | SF | Questionable | Shoulder |
Pittsburgh Steelers at Cincinnati Bengals
| Player | Pos | Team | Status | Injury |
|---|---|---|---|---|
| Kyle Dugger | S | CIN | Out | Quadricep |
| Andrei Iosivas | WR | CIN | Doubtful | Thumb |
| Brian Parker II | OT | CIN | Doubtful | Knee |
| Jalen Davis | CB | CIN | Doubtful | Hamstring |
| Derrick Harmon | DT | PIT | Questionable | Foot |
This article was drafted with AI from Pro Football News Hub data (News Hub Fantasy projections, injury reports, depth charts and the schedule) and reviewed by our editor before publishing. Read how we use AI in our editorial standards.