Deshaun Watson has owned the Titans for years, and Cleveland brings that history to Nashville as a slight favorite.

The Cleveland Browns enter Sunday, October 25, 2026 at 4-2 on a one-game winning streak. The Tennessee Titans sit at 1-5 but are also riding a one-game winning streak into kickoff at Nissan Stadium at 1:00 PM ET, with the game airing on CBS.

Game details

WhenSunday, October 25, 2026 at 1:00 PM ET
WhereNissan Stadium
TVCBS
LineCleveland Browns -2 | O/U 37 (market view)
Cleveland Browns record4-2
Tennessee Titans record1-5

The matchup

According to NFL game notes, Deshaun Watson has hit 65-plus completion percentage, thrown for 210-plus yards and tossed multiple touchdown passes in every one of his seven career starts against Tennessee, and he's got a touchdown pass in five of his past six games overall. Cleveland's last five results went win over Baltimore 13-10, loss at the Jets 12-17, win over Pittsburgh 27-24, win over Carolina 21-18 and win at Tampa Bay 23-19.

Tennessee snapped out of its funk with a 26-20 win at Indianapolis in Week 6, but before that it was a 3-26 loss to Houston, an 18-24 defeat at Baltimore, a 7-12 loss at the Giants and a 20-24 setback against Philadelphia. Cam Ward has a touchdown pass in three of his past four outings, and rookie receiver Carnell Tate caught his first career touchdown last week to go with six catches for 70 yards.

Key matchups

Watson's connection with Jerry Jeudy and rookie Denzel Boston is the engine here. Boston ranks first among rookies in receiving yards with 345 and in receiving touchdowns with 3, and he'll work against a Titans secondary that includes Cor'Dale Flott, who picked off his first pass of the season last week. Quinshon Judkins anchors the Cleveland backfield as the starting running back, and he'll lean on a line trying to establish rhythm against Jeffery Simmons, who put together 6 tackles, 2 sacks, a forced fumble and a recovered fumble in Week 6.

On the other side, Cam Ward and Tony Pollard carry Tennessee's offense, with Carnell Tate serving as the rookie's top target. Pollard is chasing his sixth straight game with 50-plus scrimmage yards. Up front, Cleveland's Maliek Collins is gunning for his fourth straight game with a sack, and linebacker Carson Schwesinger, who posted 13 tackles and a forced fumble last week, is chasing his third straight game with eight-plus tackles and a forced fumble.

Injuries that matter

Cleveland is without starting quarterback Dillon Gabriel, who is out with a back injury, along with defensive tackles Kalia Davis and Mike Hall Jr. and offensive guard Teven Jenkins, all ruled out. Linebacker Quincy Williams and cornerback Denzel Ward are both listed as questionable. Carson Schwesinger and Grant Delpit were each limited in practice, though neither carries a game status.

Tennessee lists wide receiver Calvin Ridley, linebacker Dorian Mausi, safety Kevin Winston Jr. and safety Tony Adams as questionable. Running back Tyjae Spears is also questionable, but his listing is tied to resting the player rather than an injury.

Fantasy angles

Deshaun Watson projects as the top fantasy piece on this slate at 15.0 DraftKings points, and his track record against Tennessee backs that number up. Quinshon Judkins (11.5) is in line for a heavy workload as Cleveland's lead back. Denzel Boston (10.0) is a solid flex play given his rookie-leading touchdown total. On the Titans side, Cam Ward (11.0) gives Tennessee its best fantasy option, with Carnell Tate (10.5) right behind him as the rookie's top target coming off his first career touchdown catch.

The pick

The market has Cleveland as a 2.0-point favorite with the total set at 37.0, and the market score sits at Browns 20, Titans 18. Watson's history against Tennessee and Cleveland's deeper receiving corps give the Browns the edge in what projects as a tight, low-scoring affair.

Injury report

PlayerTeamPosStatus
Dillon GabrielCleveland BrownsQBOut
Kalia DavisCleveland BrownsDTOut
Mike Hall Jr.Cleveland BrownsDTOut
Teven JenkinsCleveland BrownsOGOut
Quincy WilliamsCleveland BrownsLBQuestionable
Denzel WardCleveland BrownsCBQuestionable
Carson SchwesingerCleveland BrownsLBLimited in practice (no game status yet)
Grant DelpitCleveland BrownsSLimited in practice (no game status yet)
Calvin RidleyTennessee TitansWRQuestionable
Dorian MausiTennessee TitansLBQuestionable
Kevin Winston Jr.Tennessee TitansSQuestionable
Tony AdamsTennessee TitansSQuestionable
Tyjae SpearsTennessee TitansRBQuestionable

Depth chart

Offense

PosCleveland BrownsTennessee Titans
QBDeshaun WatsonCam Ward
RBQuinshon JudkinsTony Pollard
FBMichael Burton—
WRDenzel Boston, KC Concepcion, Jerry JeudyCarnell Tate, Wan'Dale Robinson, Elic Ayomanor
TEHarold Fannin Jr.Gunnar Helm
LTSpencer FanoDan Moore Jr.
LGZion JohnsonPeter Skoronski
CElgton JenkinsAustin Schlottmann
RGAustin BarberAtonio Mafi
RTTytus HowardJC Latham

Defense

PosCleveland BrownsTennessee Titans
LDEIsaiah McGuireJohn Franklin-Myers
LDTMason GrahamJeffery Simmons
RDTMaliek CollinsSolomon Thomas
RDEJared VerseJermaine Johnson II
WLBEaston Mascarenas-ArnoldCedric Gray
MLBCarson SchwesingerAnthony Hill Jr.
SLBQuincy WilliamsCody Barton
LCBDenzel WardCor'Dale Flott
RCBTyson CampbellJoshua Williams
NBMyles HardenMarcus Harris
SSGrant DelpitAmani Hooker
FSRonnie HickmanKevin Winston Jr.

Recent results

TeamLast games
Cleveland BrownsWk6 W 13-10 vs Baltimore Ravens, Wk5 L 12-17 vs New York Jets, Wk4 W 27-24 vs Pittsburgh Steelers
Tennessee TitansWk6 W 26-20 vs Indianapolis Colts, Wk5 L 3-26 vs Houston Texans, Wk4 L 18-24 vs Baltimore Ravens

Game page

Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our editorial standards.