Bo Nix just made history, and now the surging Denver Broncos host Patrick Mahomes and the reeling Kansas City Chiefs.
The Kansas City Chiefs are 5-1 but limp in on a one-game losing streak after a 3-20 defeat to the Seattle Seahawks. The Denver Broncos sit at 5-2 and have won three straight, the latest a 30-16 win over the Arizona Cardinals.
Game details
| When | Sunday, November 1, 2026 at 4:25 PM ET |
| Where | Empower Field at Mile High |
| TV | CBS |
| Line | Kansas City Chiefs -1 | O/U 40.5 (market view) |
| Kansas City Chiefs record | 5-1 |
| Denver Broncos record | 5-2 |
The matchup
According to NFL game notes, Bo Nix became just the fifth player in NFL history to throw a touchdown pass of at least 50 yards and rush for a touchdown of at least 50 yards in the same game. He did it in Week 7 against the Arizona Cardinals, throwing for 222 yards and a touchdown while rushing for a season-high 73 yards and another score.
Kansas City leads the all-time series 74-58, though Denver has won three of the last four meetings. The two sides opened the season against each other as well, with Mahomes throwing for 184 yards and two touchdowns and adding a rushing score as Kansas City won 31-10 on Denver's Week 1 trip to Arrowhead.
Key matchups
Patrick Mahomes is 14-2 against Denver with 4,231 passing yards and 26 total touchdowns in that stretch, and he'll test a Broncos secondary fronted by Pat Surtain II. Kenneth Walker III leads the AFC with 701 rushing yards and is tied for first in the conference with eight scrimmage touchdowns, putting him right in the middle of Kansas City's plan near the goal line.
Travis Kelce needs eleven receptions to tie Pro Football Hall of Famer Jerry Rice's 1,115 catches among players in their first 200 career games, and Denver linebacker Alex Singleton needs at least 13 tackles to join Zaire Franklin as the only players since 2000 with 100 tackles through a team's first eight games, per the NFL.
J.K. Dobbins is aiming for his fourth straight game with a rushing touchdown, putting him in the mix near Denver's goal line opposite a Kansas City front that got 11 tackles and a TFL from Nick Bolton and a season-high 12 tackles from Drue Tranquill last week.
Xavier Worthy has topped 70 receiving yards in two of his past three games, giving Mahomes another weapon against a Denver secondary that includes Ja'Quan McMillian, who is aiming for a third straight game with five-plus tackles and two-plus pass breakups.
Injuries that matter
Kansas City will have question marks on the back end, with L'Jarius Sneed (knee) and Mansoor Delane (shoulder) both listed as questionable and defensive tackle Omarr Norman-Lott (knee) ruled out. Defensive end R Mason Thomas is also questionable for a personal matter unrelated to injury.
Denver's injury report is longer. Safety Talanoa Hufanga (ankle) is out, and running back RJ Harvey (knee) won't play either. Offensive tackle Garett Bolles (hip), defensive end Zach Allen (hamstring), safety Brandon Jones (hamstring) and receiver Jaylen Waddle (chest) are all questionable.
Fantasy angles
Kenneth Walker III is a must-start, projected for 19.5 DraftKings points on the back of his league-leading rushing volume and a share of scoring near the goal line.
Patrick Mahomes projects for 16.0 points and remains a strong option given his track record in this matchup.
Travis Kelce is projected for 8.5 points, and while that's modest, his target share keeps him in lineups as he chases the receptions milestone.
Bo Nix projects for 14.0 points, with his legs adding a rushing floor after he flashed a rushing score to go with a passing touchdown last week.
Jaylen Waddle is projected for 7.0 points, but his questionable chest injury makes him a risk to confirm before locking him into lineups.
The pick
The market has Kansas City as a one-point favorite, with a projected score of Chiefs 21, Broncos 20. Mahomes' track record against Denver and Kenneth Walker III's role near the goal line give Kansas City the edge, even with Denver riding a three-game winning streak at home. Expect a tight one that comes down to who finishes drives inside the twenty.
Injury report
| Player | Team | Pos | Status |
|---|---|---|---|
| L'Jarius Sneed | Kansas City Chiefs | CB | Questionable |
| Omarr Norman-Lott | Kansas City Chiefs | DT | Out |
| Mansoor Delane | Kansas City Chiefs | CB | Questionable |
| R Mason Thomas | Kansas City Chiefs | DE | Questionable |
| Garett Bolles | Denver Broncos | OT | Questionable |
| Jaylen Waddle | Denver Broncos | WR | Questionable |
| Talanoa Hufanga | Denver Broncos | S | Out |
| Zach Allen | Denver Broncos | DE | Questionable |
| Brandon Jones | Denver Broncos | S | Questionable |
| RJ Harvey | Denver Broncos | RB | Out |
Depth chart
Offense
| Pos | Kansas City Chiefs | Denver Broncos |
|---|---|---|
| QB | Patrick Mahomes | Bo Nix |
| RB | Kenneth Walker III | J.K. Dobbins |
| FB | Ben VanSumeren | Adam Prentice |
| WR | Rashee Rice, Xavier Worthy, Jalen Royals | Jaylen Waddle, Courtland Sutton, Troy Franklin |
| TE | Travis Kelce | Evan Engram |
| LT | Kahlil Benson | Garett Bolles |
| LG | Kingsley Suamataia | Ben Powers |
| C | Creed Humphrey | Luke Wattenberg |
| RG | Trey Smith | Quinn Meinerz |
| RT | Jaylon Moore | Mike McGlinchey |
Defense
| Pos | Kansas City Chiefs | Denver Broncos |
|---|---|---|
| LDE | George Karlaftis | Zach Allen |
| LDT | Chris Jones | — |
| RDT | Khyiris Tonga | — |
| RDE | Felix Anudike-Uzomah | Eyioma Uwazurike |
| WLB | Drue Tranquill | Jonathon Cooper |
| MLB | Nick Bolton | — |
| SLB | Jeffrey Bassa | Nik Bonitto |
| LCB | Nohl Williams | Pat Surtain II |
| RCB | Mansoor Delane | Riley Moss |
| NB | L'Jarius Sneed | Ja'Quan McMillian |
| SS | Chamarri Conner | Talanoa Hufanga |
| FS | Alohi Gilman | Brandon Jones |
| NT | — | D.J. Jones |
| LILB | — | Alex Singleton |
| RILB | — | Justin Strnad |
Recent results
| Team | Last games |
|---|---|
| Kansas City Chiefs | Wk7 L 3-20 vs Seattle Seahawks, Wk6 W 22-6 vs Los Angeles Chargers, Wk4 W 30-27 vs Las Vegas Raiders |
| Denver Broncos | Wk7 W 30-16 vs Arizona Cardinals, Wk6 W 17-14 vs Seattle Seahawks, Wk5 W 23-17 vs Los Angeles Chargers |
More league notes: Week 8 NFL Preview & Capsules and What To Look For - Week 8, from the NFL.
Written by Rhett Zone, an AI analyst, from News Hub Fantasy data (schedule, scores, box scores, injuries and depth charts). A second AI checked every claim against that data before it was published. Read how we use AI in our editorial standards.